{"id":199,"date":"2025-08-13T20:28:04","date_gmt":"2025-08-13T20:28:04","guid":{"rendered":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/publications\/"},"modified":"2025-12-22T20:21:46","modified_gmt":"2025-12-22T20:21:46","slug":"publications","status":"publish","type":"page","link":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/publications\/","title":{"rendered":"The Vederas Group | Publications"},"content":{"rendered":"

Selected Recent Publications (from over 400 total):<\/p>\n

(click here for full list of publications<\/a><\/strong>)<\/p>\n

Lamer, T.; Chen, P.; Catenza, K.; Perov, I.; Donnelly, B.L.; Hsiao, Y.-T.; Van Oers, T.J.; Lemieux, M.J.; Vederas, J.C. Structure and inhibition of diaminopimelic acid epimerase by slow-binding alpha-methyl amino acids. Protein Sci. 34:e70139. 1-15 (2025).<\/p>\n

Perov, I.; Catenza, K..;Abucay, J.J.; Hsiao, Y.-T.; Vederas, J.C. Investigation and optimization of metal- and organocatalyzed decarboxylative radical addition of carboxylic acids to Seebach-Beckwith dehydroalanine towards optically pure nonnatural amino acids. Tetrahedron Lett. 159<\/strong>, 15507, 1-7 (2025).<\/p>\n

Chen, P.; Van Oers. T.J.; Arutyunova, E.; Fischer, C.; Wang, C.; Lamer, T.; van Belkum, M.J.; Young, H.S.; Vederas, J.C.; Lemieux, M.J. A structural comparison of oral SARS-CoV-2 drug candidate ibuzatrelvir complexed with the main protease (Mpro) of SARS-CoV-2 and MERS-CoV JACS Au 4, 3217-3227 (2024).<\/p>\n

Van Oers, T.J.; Piercey, A.; Belovodskiy, A.; Reiz, B.; Donnelly, B.L; Vuong, W.; Lemieux, M.J.; Nieman, J.A.; Auclair, K.; Vederas, J.C. Deuteration for Metabolic Stabilization of SARS-CoV-2 Inhibitors GC373 and Nirmatrelvir. Org. Lett. 25<\/strong>, 5885-5889 (2023)<\/p>\n

Pascoe, C.A.; Engelhardt, D.B.; Rosana, A.R.R.; van Belkum, M.J.; Vederas, J.C. Methylene Analogues of Neopetrosiamide as Potential Antimetastatic Agents: Solid Supported Syntheses Using Diamino Diacids for Pre-Stapling of Peptides with Multiple Disulfides. Org. Lett. 23<\/strong>, 9216-9220 (2021)<\/p>\n

Fernandez, K.X; Fischer, C.; Vu, Gheblawi, M.; Wang, W.; Gottschalk, S.; Iturrioz, X.; Llorens-Cort\u00e8s, C.; Oudit, G.A.; Vederas, J.C. Metabolically stable apelin-analogues, incorporating cyclohexylalanine and homoarginine, as potent apelin receptor activators RSC Med. Chem. 12<\/strong>, 1402\u20131413 (2021).<\/p>\n

Vuong, W.; Khan, M.B; Fischer, C.; Arutyunova, E.; Lamer, T.; Shields, J.; Saffran, H.A.; McKay, R.T.; van Belkum, M.J.; Joyce, M.; Young, H.S.; Tyrrell, D.L.; Vederas, J.C.; Lemieux, M.J. Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nature Comm. 11<\/strong>, Article 4282, 1-8 (2020).<\/p>\n

Acedo J.Z.; Chiorean, S.; Vederas, J.C.; van Belkum, M.J. The expanding structural variety among bacteriocins from Gram-positive bacteria. FEMS Microbiol. Rev., 42<\/strong>, 805\u2013828 (2018).<\/p>\n

<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Selected Recent Publications (from over 400 total): (click here for full list of publications) Lamer, T.; Chen, P.; Catenza, K.; Perov, I.; Donnelly, B.L.; Hsiao, Y.-T.; Van Oers, T.J.; Lemieux, M.J.; Vederas, J.C. Structure and inhibition of diaminopimelic acid epimerase by slow-binding alpha-methyl amino acids. Protein Sci. 34:e70139. 1-15 (2025). Perov, I.; Catenza, K..;Abucay, J.J.; … The Vederas Group | Publications<\/span><\/a><\/p>\n","protected":false},"author":117,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/vederas2.php","meta":{"footnotes":""},"wf_page_folders":[9],"class_list":["post-199","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/199","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/users\/117"}],"replies":[{"embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/comments?post=199"}],"version-history":[{"count":8,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/199\/revisions"}],"predecessor-version":[{"id":2396,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/199\/revisions\/2396"}],"wp:attachment":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/media?parent=199"}],"wp:term":[{"taxonomy":"wf_page_folders","embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/wf_page_folders?post=199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}