{"id":1746,"date":"2025-09-12T21:39:29","date_gmt":"2025-09-12T21:39:29","guid":{"rendered":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/outline_5\/"},"modified":"2025-09-12T21:58:53","modified_gmt":"2025-09-12T21:58:53","slug":"outline_5","status":"publish","type":"page","link":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/chem263\/outlines\/outline_5\/","title":{"rendered":"Lecture Outline 5"},"content":{"rendered":"<h1 align=\"left\">Chem 263 &#8211; Lecture Outline &amp; Assignment #5<\/h1>\n<p align=\"left\">\u00a0<\/p>\n<blockquote>\n<p><a href=\"#Readings\">Readings<\/a><br \/>\n  <a href=\"#Problems\">Problems<\/a><br \/>\n  <a href=\"#Outline\">Outline<\/a><br \/>\n  <a href=\"pdf\/C263_Out_5_and_Assign5Nov16.pdf\">Download pdf<\/a><\/p>\n<\/blockquote>\n<p align=\"left\">\u00a0<\/p>\n<h2><b><a name=\"Readings\" \/>Readings:<\/b><\/h2>\n<p \/>\n<p>TWG Solomons and CB Fryhle &#8220;Organic Chemistry&#8221; 11th Edition (2014):<\/p>\n<ul>\n<li>Functional Group List on p 76  and<\/li>\n<li>Relative Strength of Acids and Bases on Inside Front Cover &#8211; same table page 111 (page 101 9th Edition &amp; page 105 &#8211; 8th Edition<\/li>\n<li>Chapter 20 \u2013 Amines<\/li>\n<li>Chapter 24\u2013 Amino Acids and Proteins \u2013 Read for general background<\/li>\n<\/ul>\n<p align=\"right\"><a href=\"#Top\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-content\/uploads\/sites\/123\/2025\/08\/top_down.jpg\" alt=\"Top\" width=\"27\" height=\"16\" hspace=\"20\" border=\"0\" id=\"Top1\" \/><\/a>\n<\/p>\n<hr align=\"left\" width=\"100%\" \/>\n<p>\u00a0<\/p>\n<h2><b><a name=\"Problems\" id=\"Problems\" \/>Problems:<\/b><\/h2>\n<p>Do Not turn in, answers available in &#8220;Study Guide and Solutions Manual for Organic Chemistry&#8221; by Solomons and Fryhle.<\/p>\n<blockquote>\n<p><strong>Chapter 20:<br \/>\n  <\/strong> 20.1 to 20.7; 20.10; 20.13; 20.14; 20.19; 20.20<\/p>\n<\/blockquote>\n<p align=\"right\"><a href=\"#Top\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-content\/uploads\/sites\/123\/2025\/08\/top_down.jpg\" alt=\"Top\" width=\"27\" height=\"16\" hspace=\"20\" border=\"0\" id=\"Top2\" \/><\/a>\n<\/p>\n<hr align=\"left\" width=\"100%\" \/>\n<p>\u00a0<\/p>\n<h2><b><a name=\"Outline\" id=\"Outline\" \/><\/b><strong>Lecture Outline 5: Amines, Alkaloids &amp; Introduction to Amino Acids<\/strong><\/h2>\n<ol>\n<li><strong> Structure and Nomenclature of Amines<\/strong>\n<ol type=\"A\">\n<li>Nomenclature\n<ol>\n<li> Common names &#8211; heterocyclic amines <\/li>\n<li> Systematic (IUPAC)\n<\/li>\n<\/ol>\n<\/li>\n<li>Basicity of Amines and Physical Properties\n<\/li>\n<\/ol>\n<\/li>\n<li> <strong>Preparation of Amines<\/strong>\n<ol type=\"A\">\n<li> Nucleophilic Substitution Reactions (SN2) on Alkyl Halides and Sulfonates\n<\/li>\n<li>Reduction of Nitro Compounds\n<\/li>\n<li>Reductive Amination of Imines Derived from Ketones and Other Amines\n<\/li>\n<li> Reduction of Alkyl Cyanides (Nitriles) or Amides\n<\/li>\n<li> Hofmann Degradation of Amides\n<\/li>\n<li> Gabriel Synthesis\n<\/li>\n<\/ol>\n<\/li>\n<li> <strong>Reactions of Amines<\/strong>\n<ol type=\"A\">\n<li>Acid-Base Reactions\n<\/li>\n<li>Alkylation\n<\/li>\n<li> Acylation (Ammonolysis of Carboxylic Acid Derivatives to Form Amides)\n<\/li>\n<li> Reaction with Nitrous Acid \n<ol>\n<li> Aliphatic Amines <\/li>\n<li> Aromatic Amines &#8211; Reactions of Diazonium Salts\n<ol type=\"a\">\n<li> Replacement reactions <\/li>\n<li> Coupling reactions\n<p><\/p>\n<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<li><strong>Some Alkaloids in Nature and Their Importance<\/strong>\n<p>\n  <\/li>\n<li><strong>General Structure and Properties of Amino Acids and Peptides<br \/>\n  <\/strong><\/li>\n<\/ol>\n<p align=\"right\"><a href=\"#Top\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-content\/uploads\/sites\/123\/2025\/08\/top_down.jpg\" alt=\"Top\" width=\"27\" height=\"16\" hspace=\"20\" border=\"0\" \/><\/a>\n<\/p>\n<hr align=\"left\" width=\"100%\" \/>\n","protected":false},"excerpt":{"rendered":"<p>Chem 263 &#8211; Lecture Outline &amp; Assignment #5 \u00a0 Readings Problems Outline Download pdf \u00a0 Readings: TWG Solomons and CB Fryhle &#8220;Organic Chemistry&#8221; 11th Edition (2014): Functional Group List on p 76 and Relative Strength of Acids and Bases on Inside Front Cover &#8211; same table page 111 (page 101 9th Edition &amp; page 105 <a href=\"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/chem263\/outlines\/outline_5\/\" class=\"more-link\">&#8230;<span class=\"screen-reader-text\">  Lecture Outline 5<\/span><\/a><\/p>\n","protected":false},"author":117,"featured_media":0,"parent":1199,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/chem263.php","meta":{"footnotes":""},"wf_page_folders":[7],"class_list":["post-1746","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/1746","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/users\/117"}],"replies":[{"embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/comments?post=1746"}],"version-history":[{"count":3,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/1746\/revisions"}],"predecessor-version":[{"id":1763,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/1746\/revisions\/1763"}],"up":[{"embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/1199"}],"wp:attachment":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/media?parent=1746"}],"wp:term":[{"taxonomy":"wf_page_folders","embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/wf_page_folders?post=1746"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}