{"id":1742,"date":"2025-09-12T21:36:43","date_gmt":"2025-09-12T21:36:43","guid":{"rendered":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/outline_2\/"},"modified":"2025-09-12T21:46:47","modified_gmt":"2025-09-12T21:46:47","slug":"outline_2","status":"publish","type":"page","link":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/chem263\/outlines\/outline_2\/","title":{"rendered":"Lecture Outline 2"},"content":{"rendered":"<h1 align=\"left\">Chem 263 &#8211; Lecture Outline &amp; Assignment #2<\/h1>\n<p align=\"left\">\u00a0<\/p>\n<blockquote>\n<p><a href=\"#Readings\">Readings<\/a><br \/>\n  <a href=\"#Problems\">Problems<\/a><br \/>\n  <a href=\"#Outline\">Outline<\/a><br \/>\n  <a href=\"pdf\/C263_Out_2_and_Assign2Sep16.pdf\" target=\"_blank\">Download pdf<\/a><\/p>\n<\/blockquote>\n<p align=\"left\">\u00a0<\/p>\n<h2><b><a name=\"Readings\" \/>Readings:<\/b><\/h2>\n<p \/>\n<p>TWG Solomons and CB Fryhle &#8220;Organic Chemistry&#8221; 11th Edition (2014):<\/p>\n<ul>\n<li>Functional Group List on pp 76 and<\/li>\n<li>Periodic Table &#8211; Inside Front Cover (one page back from Inside Back Cover on earlier editions)<\/li>\n<li>Relative Strength of Acids and Bases on Inside Front Cover &#8211; same table page 111 (page 101 9th Edition &amp; page 105 &#8211; 8th Edition)<\/li>\n<li>Chapter 14 \u2013 Aromatic Compounds read for overview\n<ul>\n<li>study sections 14.1 to 14.10<\/li>\n<\/ul>\n<\/li>\n<li>Chapter 15 \u2013 Reactions of Aromatic Compounds<\/li>\n<li>Chapter 20 \u2013 Sections 20.1; 20.6C; 20.7; 20.8; (20.11 in 8th Ed or 20.9 in 9th Ed)<\/li>\n<li>Chapter 21 \u2013 Phenols and Aryl Halides \u2013 focus on structure, nomenclature, electrophilic reactions<\/li>\n<\/ul>\n<p align=\"right\"><a href=\"#Top\"><img loading=\"lazy\" decoding=\"async\" src=\"..\/..\/images\/top_down.jpg\" alt=\"Top\" width=\"27\" height=\"16\" hspace=\"20\" border=\"0\" id=\"Top1\" \/><\/a>\n<\/p>\n<hr align=\"left\" width=\"100%\" \/>\n<p>\u00a0<\/p>\n<h2><b><a name=\"Problems\" id=\"Problems\" \/>Problems:<\/b><\/h2>\n<p> Do Not turn in, answers available in &#8220;Study Guide and Solutions Manual for Organic Chemistry&#8221; by Solomons and Fryhle.<\/p>\n<blockquote>\n<p><strong>Chapter 14:<br \/>\n  <\/strong>practice problems 14.1; 14.3; 14.10; 14.12; 14.16; 14.17; 14.18; 14.21<\/p>\n<p><strong>Chapter 15:<br \/>\n  <\/strong>practice problems15.1; 15.2; 15.5; 15.7; 15.8; 15.11; 15.17; 15.18; 15.22a; 15.24; 15.25<\/p>\n<p><strong>Chapter 20:<br \/>\n  <\/strong>practice problems 20.10; 20.11; 20.13; 20.14<\/p>\n<p><strong>Chapter 21:<br \/>\n  <\/strong>practice problems 21.1; 21.2; 21.13; 21.14<\/p>\n<\/blockquote>\n<p align=\"right\"><a href=\"#Top\"><img loading=\"lazy\" decoding=\"async\" src=\"..\/..\/images\/top_down.jpg\" alt=\"Top\" width=\"27\" height=\"16\" hspace=\"20\" border=\"0\" id=\"Top2\" \/><\/a>\n<\/p>\n<hr align=\"left\" width=\"100%\" \/>\n<p>\u00a0<\/p>\n<h2><b><a name=\"Outline\" id=\"Outline\" \/><\/b><strong>Lecture Outline 2: Aromaticity and Reactions of Benzene Derivatives (Electrophilic Aromatic Substitution)<\/strong><\/h2>\n<ol>\n<li><strong> Review of Aromaticity, Benzene, and Nomenclature<\/strong>\n<ol type=\"A\">\n<li> Structure and Properties of Benzene\n<ol>\n<li> Resonance Stabilization <\/li>\n<li> Substitution vs. Addition Reactions\n<\/li>\n<\/ol>\n<\/li>\n<li> Annulenes and Huckel&#8217;s Rule\n<ol>\n<li> Coplanar Systems of (4n+2) pi Electrons<\/li>\n<li> Aromatic Ions &#8211; Acidity of Parent Compounds\n<\/li>\n<\/ol>\n<\/li>\n<li> Other Aromatic Systems &#8211; Naphthalene, Anthracene, and Heteroaromatic Systems\n<ol>\n<li> Five membered rings &#8211; Furan, Pyrrole, Thiophene, Imidazole <\/li>\n<li> Six membered rings &#8211; Pyridine, Pyrimidine\n<\/li>\n<\/ol>\n<\/li>\n<li> Nomenclature of Monosubstituted Benzenes\n<ol>\n<li> As Derivatives of Benzene <\/li>\n<li> Common names (Phenol, Aniline, Anisole, etc.)\n<\/li>\n<\/ol>\n<\/li>\n<li> Nomenclature of Multiply-Substituted Benzenes\n<ol>\n<li> Using Numbers and Common Names <\/li>\n<li> Ortho, Meta, Para Nomenclature\n<p>\n                <\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<li> <strong>Electrophilic Substitution Reactions<\/strong>\n<ol type=\"A\">\n<li> Benzene &#8211; General Mechanism\n<ol>\n<li>Halogenation &#8211; X2<\/li>\n<li>Nitration &#8211; HNO3<\/li>\n<li>Sulfonation &#8211; SO3 .H2SO4<\/li>\n<li>Friedel-Crafts Alkylations &#8211; Lewis Acid + RX<\/li>\n<li>Friedel-Crafts Acylations &#8211; Acylium Ions from Acid Halides \/ Anhydrides\u00a0<\/li>\n<li>Use of Clemmensen Reduction (Zn\/Hg and HCl) with Friedel-Crafts Acylation\n<\/li>\n<\/ol>\n<\/li>\n<li> Effects of Substituents\n<ol>\n<li>Activation vs. Deactivation &#8211; Electron Donating vs Electron Withdrawing Groups<\/li>\n<li>Orientation &#8211; (Ortho-Para vs. Meta)<\/li>\n<li>Inductive vs. Resonance Effects<\/li>\n<li>Disubstituted Benzene Reactions\n<p>\n          <\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n<li> <strong>Reactions of Side Chains and Substituents of Aromatic Systems<\/strong>\n<ol type=\"A\">\n<li> Nitro to Amino to Diazonium Salts\n<ol>\n<li>Reduction of Nitrobenzenes to Anilines and Diazotization (NaNO3 and HCl)<\/li>\n<li>Replacement of Diazo Group<\/li>\n<li>Azo Coupling and Dyes\n<\/li>\n<\/ol>\n<\/li>\n<li> Oxidation of Alkyl Side Chains of Aromatic Compounds to Carboxylic Acids<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<p align=\"right\"><a href=\"#Top\"><img loading=\"lazy\" decoding=\"async\" src=\"..\/..\/images\/top_down.jpg\" alt=\"Top\" width=\"27\" height=\"16\" hspace=\"20\" border=\"0\" \/><\/a>\n<\/p>\n<hr align=\"left\" width=\"100%\" \/>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chem 263 &#8211; Lecture Outline &amp; Assignment #2 \u00a0 Readings Problems Outline Download pdf \u00a0 Readings: TWG Solomons and CB Fryhle &#8220;Organic Chemistry&#8221; 11th Edition (2014): Functional Group List on pp 76 and Periodic Table &#8211; Inside Front Cover (one page back from Inside Back Cover on earlier editions) Relative Strength of Acids and Bases <a href=\"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/chem263\/outlines\/outline_2\/\" class=\"more-link\">&#8230;<span class=\"screen-reader-text\">  Lecture Outline 2<\/span><\/a><\/p>\n","protected":false},"author":117,"featured_media":0,"parent":1199,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/chem263.php","meta":{"footnotes":""},"wf_page_folders":[7],"class_list":["post-1742","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/1742","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/users\/117"}],"replies":[{"embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/comments?post=1742"}],"version-history":[{"count":2,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/1742\/revisions"}],"predecessor-version":[{"id":1751,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/1742\/revisions\/1751"}],"up":[{"embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/pages\/1199"}],"wp:attachment":[{"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/media?parent=1742"}],"wp:term":[{"taxonomy":"wf_page_folders","embeddable":true,"href":"https:\/\/spaces.facsci.ualberta.ca\/vederaslab\/wp-json\/wp\/v2\/wf_page_folders?post=1742"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}