Current Lab Members

Kejia YanKejia Yan

GRADUATE STUDENT

  • B.Sc., Engineering, Pharmaceutical Engineering, Zhejiang University of Technology, 2017
  • M.Sc., Pharmaceutical Science and Life Science, Hoshi University, 2019
  • Ph.D. candidate in Derda Lab since Sept. 2019
Click to see more about Kejia...

Kejia Yan is developing chemical strategies for the synthesis of genetically-encoded libraries and uses them to answer fundamental questions in chemical reactivity.

Jeffrey (Ying Kit) Wong Jeffrey (Ying Kit) Wong

GRADUATE STUDENT

  • B.Sc., University of Alberta (2016)
  • PhD Candidate in Derda Lab since Sept. 2016

 

Click to see more about Jeffrey...

Jeffrey is employing genetically-encoded chemical libraries to identify early drug leads that inhibit anti-tumor protein Nodal

Guilherme Meira LimaGuilherme Meira Lima

GRADUATE STUDENT

  • M.Sc., University of São Paulo (USP), São Paulo, Brazil. Pharmaceutical Technology Program, 2019
  • B.Sc., University of São Paulo (USP), São Paulo, Brazil. Bachelor of Science: Pharmacy and Biochemistry, 2018
  • Graduate student in Derda Lab since Sept. 2019
Click to see more about Guilherme...

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Mirat SojitraMirat Sojitra

GRADUATE STUDENT

  • B.Sc., University of Alberta 2017
  • Graduate student in Derda Lab since Jan. 2018
Click to see more about Mirat...

Mirat is working on genetically-encoded chemical libraries, discovery of instructive biomaterials and Liquid Glycan Array (LiGA) technology

Publication from Derda Lab:

  1. Mirat SojitraSusmita SarkarJasmine MagheraEmily RodriguesEric J. CarpenterShaurya SethDaniel Ferrer VinalsNicholas J. BennettRevathi ReddyAmira Khalil, Xiaochao XueMichael BellRuixiang Blake ZhengPing ZhangChang Chun Ling, Todd L. LowaryJames C. PaulsonMatthew S. Macauley, Ratmir Derda* “Genetically Encoded, Multivalent Liquid Glycan Array (LiGA)“, BioRXiv, 2020, DOI: 10.1101/2020.03.24.997536

RevathiRevathi Reddy

GRADUATE STUDENT

  • B.Sc., Pharmaceutical Sciences, Institute of Chemical Technology, Mumbai, India
  • Graduate student in Derda Lab since Sep. 2018
  • Graduate student mentor for the UAlberta 2019 iGEM team
Click to see more about Revathi...

Revathi is working on genetically-encoded Liquid Glycan Array (LiGA) technology and its application in serological tests. Her awards include: Bronze medal at the International Genetically Engineered Machine (iGEM) competition in Boston for the project “Engineering E.coli for ammonia assimilation from public urinals”. As the Communications Officer of the Glyconet Trainee Association, Revathi moderates and writes for the CuriOSEity blog [1] [2] [3]. She also develops resources for the Synthetic Biology community by creating digital content [4] and organizing science communication training programs [5]

References:

Chih Lan (Tracy) LinChih Lan (Tracy) Lin

GRADUATE STUDENT (co-supervised)

  • B.Sc., National Tsing Hua University (Hsinchu, Taiwan)
  • M.Sc., Organic Chemistry, National Tsing Hua University (Hsinchu, Taiwan)
  • Graduate student in Lowary and Derda Lab since Sep. 2018
Click to see more about Tracy...

Tracy is working on chemo-enzymetic synthesis of complex glycans and their application in genetically-encoded Liquid Glycan Array (LiGA) technology

Arunika Ekanayake

POSTDOCTORAL FELLOW

  • PhD in Chemistry, University of Southern California
  • B.S. in Biochemistry and Molecular Biology (First class honors), University of Colombo, Sri Lanka
Click to see more about Arunika...

Arunika is developing new genetically encoded chemical spaces and uses them to discover new classes reversible covalent inhibitors of proteins

Publications from Derda Lab

Arunika Ekanayake, Lena Sobze, Jihea Youk, Nicholas J. Bennett, Raja Mukherjee, Atul Bhardwaj, Frank Wuest, Ratmir Derda, “Genetically Encoded Fragment-Based Discovery (GE-FBD) from Phage-Displayed Macrocyclic Libraries with Genetically-Encoded Unnatural Pharmacophores ChemRxiv. Preprint., 2020 DOI: 10.26434/chemrxiv.12644225.v1

Mike Downey

POSTDOCTORAL FELLOW

  • MS, University of Alberta
  • PhD, Charles University, Prague
  • PDF, Max Planck Institute, Seeberger Lab
  • Postdoctoral Fellow in Derda Lab since 2021
Click to see more about Mike..

Mike is working in the area of immunooncology therapeutics and inhibitors of Siglec proteins

Ganesh SableGanesh Sable

POSTDOCTORAL FELLOW

  • PhD, Sejong University, Seoul, Republic of Korea. (Advisor: Dongyeol Lim)
  • Research Assistant Professor, POSTECH (PI: Prof. Hyun Suk Lim)
  • Scientific Collaborator, EPFL (PI: Prof. Christian Heinis)
  • Postdoctoral Fellow in Derda Lab since 2020
Click to see more about Ganesh..

Ganesh develops chemically-modified peptide libraries with applications to development of imaging agents and therapeutic candidates (collaboration with Frank Wuest and Todd McMullen)

Alexei AtrazhevAlexey Atrazhev

RESEARCH ASSOCIATE

  • PhD in Chemistry, Moscow State University
  • B.S. in Chemistry, Moscow State University
Click to see more about Alexei...

Alexei is developing new classes of phage vectors to enable display, discovery and detection that is impossible with state-of-the-art display systems

Eric CarpenterEric Carpenter

RESEARCH ASSISTANT (joint with Greiner Lab)

  • B.S. with honors in physics, University of Alberta
  • Research Assistant in Derda Lab and Russ Greiner Lab since 2019
Click to see more about Eric...

Eric employs Bioinformatics and Machine Learning technologies to understand and predict interactions between proteins and glycans.

Publication from Derda Lab:

  1. Mirat SojitraSusmita SarkarJasmine MagheraEmily RodriguesEric J. CarpenterShaurya SethDaniel Ferrer VinalsNicholas J. BennettRevathi ReddyAmira Khalil, Xiaochao XueMichael BellRuixiang Blake ZhengPing ZhangChang Chun Ling, Todd L. LowaryJames C. PaulsonMatthew S. Macauley, Ratmir Derda* “Genetically Encoded, Multivalent Liquid Glycan Array (LiGA)“, BioRXiv, 2020, DOI: 10.1101/2020.03.24.997536

Noel YueNoel Yue

UNDERGRADUATE STUDENT

  • Undergraduate Research Fellow in Derda Lab since 2019
  • B.Sc., University of Alberta, 2020
  • Research Fellow, 2020
Click to see more about Noel..

Noel is semploying machine learning technologies to understand protein glycan interations.

 

Jared Zhang

UNDERGRADUATE STUDENT

  • Summer Undergraduate Fellow, 2021
  • Undergraduate research assistant in Derda Lab since 2021
Click to see more about Jared..

Jared is working on predictive AI models of protein-carbohydrate interactions.

Publications from Derda Lab

TBD

 

Ryan Qiu

UNDERGRADUATE STUDENT

  • Summer Undergraduate Fellow, 2021
  • Undergraduate research assistant in Derda Lab since 2021
Click to see more about Ryan..

Ryan is working in the area of immunooncology therapeutics and inhibitors of Siglec proteins

Ellen Hayhoe

UNDERGRADUATE STUDENT

  • Summer Undergraduate Fellow, 2021
  • Undergraduate research assistant in Derda Lab since 2020
Click to see more about Ellen..

Ellen is combining experimental and data science approaches to build the GlyNet Neural Net and Liquid Glycan Array (LiGA) technology

Elizabeth VolkerElizabeth Volker

UNDERGRADUATE STUDENT

  • Summer Undergraduate Fellow, 2020
  • Undergraduate research assistant in Derda Lab since 2020
Click to see more about Elizabeth..

Elizabeth is using parallel phage culture and expansion to build the foundation of the Liquid Glycan Array (LiGA) technology


SVEKY2SVEKY

LAB CHOW CHOW

Chow Chow Officer (CCO) of Derda Lab since July 2017

www.instagram.com/sveky.chow.chow

Click to see more about SVEKY...

SVEKY (a.k.a. Ser-Val-Glu-Lys-Tyr) joined Derda Lab in June 2017 as a 3 months old puppy and quickly rose through the ranks to become the CCO of Derda Lab. She has been named after a peptide sequence SVEKNDQKTYHA featured in numerous publications from Derda Lab:

1. V. Triana, R. Derda*, “Tandem Wittig / Diels-Alder Diversification of Genetically Encoded Peptide Libraries“, Org. Biomol. Chem.2017, 15, 7869-7877

2. Y. Chou, E. N. Kitova , M. Joe, R. Brunton, T. L. Lowary, J. S. Klassen, R. Derda*, “Genetically-encoded fragment-based discovery (GE-FBD) of glycopeptide ligands with differential selectivity for antibodies related to mycobacterial infections“, Org. Biomol. Chem2018, 16, 223 – 227

3. S Ng, MR Jafari, W Matochko, R Derda* “Quantitative Synthesis of Genetically Encoded Glycopeptide Libraries Displayed on M13 Phage” ACS Chem. Biol.2012, 7 (9), 1482–1487

4. K. F. Tjhung, F. Deiss, J. Tran, Y. Chou, R. Derda*, “Intra-domain phage display (ID-PhD) of peptides and mini-domain proteins censored from canonical pIII phage display2015 Front. Microbiol6:340.

5. S. Ng, K. F., Tjhung, B. M. Paschal, C. J. Noren, R. Derda*, “Chemical Posttranslational Modification of Phage-Displayed Peptides“, Methods in Molecular Biology, Volume 1248, 2015, pp 155-172

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Welcome to Centennial Centre for Interdisciplinary Science (CCIS), home of Derda Lab

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SVEKY in the office working on water quality detection

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SVEKY says “Always wear eye protection when working in the lab”

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SVEKY, the CCO: hard day at work..

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SVEKY measuring its melting point

High-School Outreach with Harry Ainlay School

2017-2018: Zanib Pannu*,  Yi Meng Wang*, Jesse Lee *Sanofi BioGenius Canada 2018

Click to see more about Zanib, Yi Meng, and Jesse...

Zanib Pannu and  Yi Meng Wang, joined the lab in October 2017 and worked on project that aims to identify ice-nucleating bacteria and peptides. The team participated in 2018 Sanofi Biogenius Canada competition at the University of Alberta in April, 2018.

Jesse Lee joined the project for a few months in summer 2018 and helped developing emulsion-based screening for ice nucleators

2016-2017: Simran Dhillon*, Siddhant Gautam*, Denny Zhang* and Andre Truksa *Sanofi BioGenius Canada 2017 

Click to see more about Simran, Siddhant, Denny and Andre...

Simran Dhillon, Siddhant Gautam, and Xibu (Denny) Zhang joined the lab in October 2016 and worked on project that aims to identify ice-suppressing peptides. The team participated in 2017 Sanofi Biogenius Canada competition at the University of Calgary on April 13th, 2017.

Andre Truksa joined the project in May 2017

2014-2016: Rifah Chowdhury, Preet Lat, Garrett Corkey and Hallie Trono

Click to see more about Rifah, Preet, Garrett and Hallie...

High School students Rifah Chowdhury, Preet Lat joined Derda Lab as research volunteers in Fall 2014 and they worked on development of portable diagnostics for detection of antibiotics resistant bacteria.

In Fall 2015 to Fall 2016, Rifah Chowdhury, Preet Lat and two new high school students Garrett Corkey and Hallie Trono volunteer in the Derda Lab in a research project that aimed to identify materials that trigger freezing of supercooled water.

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In 2017 Rifah Chowdhury and  Preet Lat graduate from high school and joined University of Alberta for their undergraduate studies. Preet continues her research volunteer position in Derda group working on phage-based selection of ice nucleation agents.

2013-2015: Patricia Yan and Amy Li *Sanofi BioGenius Canada 2015 winners

Click to see more about Patricia and Amy...

Fall 2013 to Spring 2015, Patricia Yan and Amy Li, high school students from Harry Ainlay High School, volunteer in the Derda Lab. They were involved in the development of the electrochemical detection of bacteria in paper-based culture devices. Patricia Yan and Amy Li were the winners of the  Sanofi BioGenius Canada competition in 2015 (1st and 2nd place at the All-Alberta competition!) and they represented Alberta in all-Canadian Sanofi BioGenius competition.

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Amy Patricia Freddie

2012-2014 Jessica Wickware* and Falak Shah *Sanofi BioGenius Canada 2014 winner

Click to see more about Jessica and Falak...

Jessica and Falak joined the group in 2012 and worked on portable bacteria culture devices. In 2014, Jessica worked on paper based culture of cancer cells. In 2014, Jessica was a winner of Sanofi BioGenius Canada all-Alberta competition and represented Alberta on All-Canadian Sanofi BioGenius competition. Jessica started her undergraduate degree at the university of Alberta in 2014 and she continued her undergraduate research project in Derda Lab. From 2014 to 2017, she supervised research projects of over 10 high school students.

2011-2012 Ally Wu, Eszter Szepesvari, Pavitra Rajendran, Nicholas Kwan-Wong

Click to see more about Ally, Eszter, Pavitra and, Nick...

Fall 2011 to Summer 2012, four high school students–Ally Wu, Eszter Szepesvari, Pavitra Rajendran, Nicholas Kwan-Wong–were involved in development of portable diagnostic devices for developing countries. They were co-authors on the manuscript in Lab on a Chip:

MF Huacca, A Wu, E Szepesvari, P Rajendran, N Kwan-Wong, A Razgulin, Y Shen, J Kagira, R Campbell, R Derda* “Portable cultures for phage and bacteria made of paper and tapeLab Chip2012, 12, 4269-4278

Ally, Eszter, Pavitra, and Nick continue their undergraduate degree at the University of Alberta.

Derda Lab High School-Students